Efficacy of Integrase Strand Transfer Inhibitors and the Capsid Inhibitor Lenacapavir against HIV-2, and Exploring the Effect of Raltegravir on the Activity of SARS-CoV-2
Retroviruses perpetuate their survival by incorporating a copy of their genome into the host cell, a critical step catalyzed by the virally encoded integrase.The viral capsid plays an important role during the viral life cycle, including nuclear importation in the case emtek 2113 of lentiviruses and integration targeting events; hence, targeting th